These handouts suggest the type of research study that should be used to answer a specific type of EBM question and the level of evidence those studies should be.
The Well Built Clinical Question - University of South Alabama Biomedical Library - Summary of the type of question, the suggested best type of study you will need to answer the question, and the appropriate level of evidence the specific studies should be.Five Steps of EBM - Robert B. Greenblatt, M.D. Library Medical College of Georgia - Another perspective on seeking information to answer a specific type of EBM question, the type and level of evidence those studies would require.
Full-text evidence-based medicine databases
Cochrane Library - The Cochrane Library consists of a regularly updated collection of evidence-based medicine databases. Look at:
Cochrane Database of Systematic Reviews - Reflects the current practice in medicine to base clinical decisions on accumulated evidence from the primary medical literature. Includes the full text of the regularly updated systematic reviews of the effects of healthcare prepared by The Cochrane Collaboration.
Cochrane Central Register of Controlled Trials (CCTR) - CCTR is a bibliographic database of definitive controlled trials. These controlled trials have been identified by the distinguished contributors to the Cochrane Collaboration.
Database of Abstracts of Reviews of Effectiveness (DARE) - A full text database containing critical assessments of systematic reviews from a variety of medical journals.
ACP Journal Club - Contains full-text evidence-based article reviews from two journals, ACP Journal Club and Evidence-Based Medicine, with enhanced abstracts and expert commentaries to both methodologically sound and clinically relevant articles from top journals.
UpToDate - A practical clinical reference providing instant access to thousands of original topic reviews written by a recognized faculty of experts who each address a specific clinical issue and provide detailed recommendations. (ONLY accessible from UPHS and School of Medicine locations, NO remote access)