A systematic review identifies an intervention for a specific disease or other problem in health care, and determines whether or not this intervention works. To do this authors locate, appraise and synthesize evidence from as many relevant scientific studies as possible. They summarize conclusions about effectiveness, and provide a unique collation of the known evidence on a given topic, so that others can easily review the primary studies for any intervention.
Systematic reviews differ from other types of review in that they adhere to a strict design in order to make them more comprehensive, thus minimizing the chance of bias, and ensuring their reliability. Rather than reflecting the views of the authors, or being based on a partial selection of the literature, (as is the case with many articles and reviews that are not explicitly systematic), they contain all known references to trials on a particular intervention and a comprehensive summary of the available evidence. The reviews are therefore also valuable sources of information for those receiving care, as well as for decision makers and researchers.
Search for specific articles by subject, author, journal, and/or author address, as well as for articles that cite a known author or work.
The premier source for bibliographic coverage of biomedical literature. MEDLINE encompasses information from Index Medicus, Index to Dental Literature, and International Nursing Index, as well as other sources of coverage in the areas of allied health, biological and physical sciences, humanities and information science as they relate to medicine and health care, communication disorders, population biology, and reproductive biology. Resources in all languages are represented.
Search for specific articles by subject, author, journal, and/or author address, as well as for articles that cite a known author or work.
This is a pilot project. Essentially the NLH Question-Answering service seeks to answer questions that health professionals have been unable to answer for themselves.
Databases that contain biomedical literature which can be applied to clinical questions.
Medline (complete file) - The premier database for bibliographic coverage of clinical and biomedical literature.
PubMed Plus - PubMed is the public access version to Medline, the premier database for biomedical literature. PubMedPlus is an enhanced version with links to full-text journals that the Penn Library subscribes to.


